4.5 Review

Organocatalyzed enantioselective desymmetrization of aziridines and epoxides

Journal

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 9, Issue -, Pages 1677-1695

Publisher

BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.9.192

Keywords

aziridine; desymmetrization; enantioselectivity; epoxide; organocatalysis

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Enantioselective desymmetrization of meso-aziridines and meso-epoxides with various nucleophiles by organocatalysis has emerged as a cutting-edge approach in recent years. This review summarizes the origin and recent developments of enantioselective desymmetrization of meso-aziridines and meso-epoxides in the presence of organocatalysts.

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