Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 11, Issue 4, Pages 397-402Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-440X(00)00223-2
Keywords
-
Categories
Funding
- NIGMS NIH HHS [GM63919, GM59164] Funding Source: Medline
Ask authors/readers for more resources
Membrane proteins can be extremely stable in a bilayer environment, but are often unstable and rapidly lose activity after detergent solubilization. Poor stability can preclude the detailed characterization of many membrane proteins. One way to alleviate this problem is to find more stable mutants of a membrane protein of interest. This approach is made tractable by the finding that stability-enhancing mutations appear to be relatively common in membrane proteins.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available