4.5 Article

Asymmetric Bronsted acid-catalyzed aza-Diels-Alder reaction of cyclic C-acylimines with cyclopentadiene

Journal

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 8, Issue -, Pages 1819-1824

Publisher

BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.8.208

Keywords

BINOL phosphate; [4+2] cycloaddition; Diels-Alder reaction; organocatalysis

Funding

  1. DFG priority programme Organocatalysis

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A new chiral Bronsted acid-catalyzed aza-Diels-Alder reaction of cyclic C-acylimines with cyclopentadiene has been developed. The reaction provides optically active aza-tetracycles in good yields with high diastereo- and enantioselectivities under mild reaction conditions.

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