Journal
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 7, Issue -, Pages 582-595Publisher
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.7.68
Keywords
asymmetric synthesis; organolithium; sulfur; substitution; thiol
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Funding
- Royal Society of Chemistry
- Hickinbottom Fellowship
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Enantiomerically pure tertiary thiols provide a major synthetic challenge, and despite the importance of chiral sulfur-containing compounds in biological and medicinal chemistry, surprisingly few effective methods are suitable for the asymmetric synthesis of tertiary thiols. This review details the most practical of the methods available.
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