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Gold-catalyzed propargylic substitutions: Scope and synthetic developments

Journal

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 7, Issue -, Pages 866-877

Publisher

BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.7.99

Keywords

direct substitutions; gold; isoxazolines; propargylic substitutions

Funding

  1. CNRS
  2. Institut de Chimie des Substances Naturelles (Gif sur Yvette)
  3. MESR
  4. Ecole Nationale Superieure de Chimie de Montpellier

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This personal account summarizes our recent developments in gold-catalyzed direct substitutions on propargylic (allylic, benzylic) alcohols, with various nucleophiles (and bi-nucleophiles) based on the sigma- and/or pi-acidity of gold(III) complexes. Synthetic developments are also briefly described.

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