4.5 Article

Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution

Journal

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 7, Issue -, Pages 1508-1515

Publisher

BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.7.176

Keywords

chemosensor; D-cysteine; enantioselectivity; fluorescence; ratiometric

Funding

  1. University Grants Committee of the Hong Kong SAR, China [HKBU 200208]

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A ratiometric fluorescent probe based on a Cd(2+)-ACAQ complex was designed and demonstrated for the chemo- and enantioselective detection of cysteine in 99:1 buffered HEPES:ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an enantioselectivity of 3.35 can be achieved for antipodal forms of Cys.

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