Journal
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 5, Issue -, Pages -Publisher
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.5.56
Keywords
asymmetric synthesis; continuous flow; diarylmethanols; solid-supported catalyst; triarylboroxins
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Funding
- ICIQ foundation
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A continuous flow system for the synthesis of enantioenriched diarylmethanols from aldehydes is described. The system uses an amino alcohol-functionalized polystyrene resin as the catalyst, and the arylating agent is conveniently prepared by transmetallation of triarylboroxins with diethylzinc.
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