Journal
NEUROREPORT
Volume 12, Issue 11, Pages 2605-2607Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200108080-00062
Keywords
right frontal cortex; right parietal cortex; neglect; TMS; visuo-spatial perception timing
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In a recent study we showed that repetitive transcranial magnetic stimulation (rTMS) with train duration of 400 ms over right frontal and right posterior parietal cortices gives rise to transitory contralateral visuo-spatial neglect in normal subjects. In the present experiment we investigated whether using single-pulse TMS it is possible to obtain information about the timing of cortical activity related to spatial cognition. Nine healthy subjects performed in baseline condition and during TMS a tachistoscopic task, requiring a forced-choice estimation of the length of the two segments of prebisected horizontal lines. Single-pulse TMS was triggered at various time intervals (150 ms, 225 ms, 300 ms) after visual stimulus onset with a focal coil over P6 and F4 (according to 10/20 EEG system). Relative transitory rightward bias was observed only when parietal TMS was delivered 150ms after visual stimulus presentation. Frontal stimulation induced no effect on visuo-spatial perception with the time intervals explored. NeuroReport 12:2605-2607 (C) 2001 Lippincott Williams & Wilkins.
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