4.8 Article

Improved chemical synthesis of UDP-galactofuranose

Journal

ORGANIC LETTERS
Volume 3, Issue 16, Pages 2517-2519

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol016170d

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Funding

  1. NIGMS NIH HHS [GM20582] Funding Source: Medline

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[GRAPHICS] A reliable and efficient synthetic route to UDP-alpha -D-galactofuranose (UDP-Galf) has been developed. Reaction of UMP-N-methylimidazolide with Galf 1-phosphate proceeds rapidly to provide UDP-Galf with excellent reproducibility and in a yield approximately twice as high as those reported previously.

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