Journal
FEBS LETTERS
Volume 503, Issue 1, Pages 1-6Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0014-5793(01)02686-2
Keywords
zinc ion; iron ion; metallo-hydrolase; beta-lactamase fold
Ask authors/readers for more resources
Recently, the zinc metallo-hydrolase family of the beta -lactamase fold has grown quite rapidly, accompanied by the accumulation of sequence and structure data. The variety of the biological functions of the family is higher than expected. In addition, the members often have mosaic structures with additional domains. The family includes class B beta -lactamase, glyoxalase II, arylsulfatase, flavoprotein, cyclase/dehydrase, an mRNA 3 ' -processing protein, a DNA cross-link repair enzyme, a DNA uptake-related protein, an alkylphosphonate uptake-related protein, CMP-N-acetylneuraininate hydroxylase, the romA gene product, alkylsulfatase, and insecticide hydrolases. In this minireview, the functional and structural varieties of the growing protein family are described. (C) 2001 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available