Journal
BRITISH JOURNAL OF CANCER
Volume 85, Issue 4, Pages 490-492Publisher
NATURE PUBLISHING GROUP
DOI: 10.1054/bjoc.2001.1969
Keywords
breast cancer; growth kinetics; micrometastases; surgery signals; tumour dormancy
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Surgery should be considered as a major perturbing factor for metastasis development in laboratory animals. The different time distribution of mortality for 1173 patients undergoing mastectomy in comparison with 250 untreated patients suggests that primary tumour removal could result in changes of the metastatic process even for breast cancer. (C) 2001 Cancer Research Campaign.
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