Journal
TETRAHEDRON LETTERS
Volume 42, Issue 34, Pages 5917-5919Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(01)01139-X
Keywords
ionic liquid; Biginelli reaction; 3,4-dihydropyrimidin-2(1H)-ones; one-pot process
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3,4-Dihydropyrimidin-2(IH)-ones were synthesised in high yields by one-pot three-component Biginelli condensation in the presence of room temperature ionic liquids such as 1-n-butyl-3-methylimidazolium tetrafluoroborate (BMImBF(4)) or hexafluorophosphorate (BMImPF(6)) as catalysts under solvent-free and neutral conditions. (C) 2001 Elsevier Science Ltd. All rights reserved.
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