4.4 Article

Practical alternatives for the synthesis of β-iodofurans by 5-endo-dig cyclisations of 3-alkyne-1,2-diols

Journal

TETRAHEDRON LETTERS
Volume 42, Issue 34, Pages 5945-5948

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(01)01112-1

Keywords

iodocyclisation; 5-endo-dig; beta-iodofurans; 3-alkyne-1,2-diols; furans

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Iodocyclisations of 3-alkyne-1,2-diols, obtained from acetylides and a-hydroxy-ketones or esters, give generally excellent yields of beta -iodofurans by 5-endo-dig cyclisation followed by dehydration. (C) 2001 Elsevier Science Ltd. All rights reserved.

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