Journal
JOURNAL OF PLANT GROWTH REGULATION
Volume 20, Issue 3, Pages 281-291Publisher
SPRINGER
DOI: 10.1007/s003440010026
Keywords
auxin-responsive gene expression; ARF genes; ARF proteins; Aux/IAA proteins
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Auxin response factors (ARFs) are a family of transcription factors that are unique to plants and bind with specificity to auxin response elements (AuxREs) in promoters of primary or early auxin response genes. ARF's have a modular structure with an amino-terminal DNA binding domain, a centralized activation or repression domain, and, in most cases, a carboxy-terminal dimerization domain. The dimerization domain in ARF proteins is related in amino sequence to the dimerization domain in Aux/IAA proteins. Homotypic and heterotypic interactions can occur between ARF and Aux/IAA protein family members. Recent biochemical and genetic studies suggest that the ARF and Aux/IAA proteins play pivotal and concerted roles in regulating the expression of primary/early auxin-responsive genes.
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