Journal
BEHAVIOURAL BRAIN RESEARCH
Volume 227, Issue 2, Pages 376-379Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbr.2011.05.012
Keywords
Hippocampal neurogenesis; Radiation; Chemotherapy; White matter; Late effects; Chemobrain
Categories
Funding
- National Institutes of Health, National Institute of Neurological Disorders and Stroke (NINDS) [1K08NS070926 - 01]
- Paul Calabresi Career Development Award for Clinical Oncology
- Stephen E. and Catherine Pappas Foundation
Ask authors/readers for more resources
Cancer therapies frequently result in a spectrum of neurocognitive deficits that include impaired learning, memory, attention and speed of information processing. Damage to dynamic neural progenitor cell populations in the brain are emerging as important etiologic factors. Radiation and chemotherapy-induced damage to neural progenitor populations responsible for adult hippocampal neurogenesis and for maintenance of subcortical white matter integrity are now believed to play major roles in the neurocognitive impairment many cancer survivors experience. (C) 2011 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
