Journal
JOURNAL OF MOLECULAR RECOGNITION
Volume 14, Issue 5, Pages 261-268Publisher
JOHN WILEY & SONS LTD
DOI: 10.1002/jmr.544
Keywords
SPR; evanescent wave; refractometry; protein array; drug discovery
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The field of commercial optical biosensors. is rapidly evolving, with new systems and detection methods being developed each year. This review outlines the currently available biosensor hardware and highlights unique features of each platform. Affinity-based biosensor technology, with its high sensitivity, wide versatility and high throughput, is playing a significant role in basic research, pharmaceutical development, and the food and environmental sciences. Likewise, the increasing popularity of biosensors is prompting manufacturers to develop new instrumentation for dedicated applications. We provide a preview of some of the emerging commercial systems that are dedicated to drug discovery, proteomics, clinical diagnostics and routine biomolecular interaction analysis. Copyright (C) 2001 John Wiley & Sons, Ltd.
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