Journal
MEDICAL IMAGE ANALYSIS
Volume 5, Issue 3, Pages 185-194Publisher
ELSEVIER
DOI: 10.1016/S1361-8415(01)00039-1
Keywords
3D segmentation; deformable models; level sets; volume registration; brain MRI
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This paper presents a strategy for the segmentation of brain from volumetric MR images which integrates 3D segmentation and 3D registration processes. The segmentation process is based on the level set formalism. A closed 3D surface propagates towards the desired boundaries through the iterative evolution of a 4D implicit function. In this work, the propagation relies on a robust evolution model including adaptive parameters. These depend on the input data and on statistical distribution models. The main contribution of this paper is the use of an automatic registration method to initialize the surface, as an alternative solution to manual initialization, The registration is achieved through a robust multiresolution and multigrid minimization scheme. This coupling significantly improves the quality of the method, since the segmentation is faster, more reliable and fully automatic. Quantitative and qualitative results on both synthetic and real volumetric brain MR images are presented and discussed. (C) 2001 Elsevier Science B.V. All rights reserved.
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