Journal
BEHAVIOURAL BRAIN RESEARCH
Volume 221, Issue 1, Pages 304-306Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbr.2011.02.048
Keywords
Anti-Mullerian hormone; Play behavior; Development; Male; Natal dispersal
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Funding
- Royal Society of New Zealand
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Male mouse pups exhibit elevated preference for novelty relative to their sisters. The testes of pups secrete high levels of Mullerian inhibiting substance (MIS, anti-Mullerian hormone), with neurons being a target of this hormone. We report here that male pups exhibit novelty preference, but their Mis(-/-) brothers and Mis(+/+) sisters do not. This suggests that MIS is one of the determinants of boy-specific behavior. (C) 2011 Elsevier B.V. All rights reserved.
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