Journal
BEHAVIOURAL BRAIN RESEARCH
Volume 220, Issue 2, Pages 362-366Publisher
ELSEVIER
DOI: 10.1016/j.bbr.2011.02.027
Keywords
Lateral septum; Anxiety; Rat; Neophagia; Novelty induced suppression of feeding
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Funding
- Natural Sciences and Engineering Research Council of Canada (NSERC)
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Past studies have shown that the lateral septum is involved in anxiety. Here, we tested whether the dorsal lateral septum contributes to neophagia by using the novelty induced suppression of feeding (NISF) paradigm. We found that while lesions of the dorsal lateral septum did not affect home or novel cage responding in the NISF test, they did decrease open arm avoidance in the elevated plus maze and burying in the shock probe burying test. Our results suggest that the dorsal lateral septum does not regulate neophagia in the NISF, but further experiments are needed to determine if the same is true for the intermediate and ventral lateral septum. (C) 2011 Elsevier B.V. All rights reserved.
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