Journal
BEHAVIOURAL BRAIN RESEARCH
Volume 213, Issue 1, Pages 109-112Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbr.2010.04.011
Keywords
Adolescence; Periadolescence; Sucrose; Cue-Induced Reinstatement; Extinction; Incubation
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Previously we reported that time-dependent increases in cue-induced reinstatement of cocaine seeking were attenuated in rats self-administering cocaine as adolescents, compared with adults (Li and Frantz (2009) [12]). Now using sucrose self-administration, we report time-dependent increases in cue-induced reinstatement of sucrose seeking are similar across age groups, suggesting that age differences in reinstatement of cocaine seeking depend on specific effects of cocaine, not a compromised ability among younger rats to associate cues with rewards. (C) 2010 Elsevier B.V. All rights reserved.
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