4.8 Article

Regiospecific synthesis of 4-(2-oxoalkyl)pyridines

Journal

ORGANIC LETTERS
Volume 3, Issue 18, Pages 2807-2809

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol010116f

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[GRAPHICS] A new and operationally simple method has been developed for the regiospecific syntheses of 4-(2-oxoalkyl)pyridines from ketones and pyridine in good yields, using triflic anhydride to activate the pyridine ring.

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