Journal
NEUROLOGY
Volume 57, Issue 5, Pages 927-929Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.57.5.927
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The authors evaluated the long-term clinical outcome of neurosarcoidosis and determined predictive factors of disease course. Twenty-seven patients with neurosarcoidosis were followed for at least 5 years from the onset of neurologic symptoms. Patients with CNS involvement during the course of the disease had a higher Modified Oxford Handicap Scale score than those with peripheral nervous system involvement (p < 0.02). CNS involvement may be a predictive factor for a less favorable disease course. Early and intensive treatment should be considered in such cases.
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