4.8 Article

Fish scale development: Hair today, teeth and scales yesterday?

Journal

CURRENT BIOLOGY
Volume 11, Issue 18, Pages R751-R752

Publisher

CELL PRESS
DOI: 10.1016/S0960-9822(01)00438-9

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A group of genes in the tumour necrosis factor signalling pathway are mutated in humans and mice with ectodermal dysplasias - a failure of hair and tooth development. A mutation has now been identified in one of these genes, ectodysplasin-A receptor, in the teleost fish Medaka, that results in a failure of scale formation.

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