Journal
NEUROSCIENTIST
Volume 7, Issue 5, Pages 455-468Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/107385840100700514
Keywords
human spinal cord injury; locomotor training; neural plasticity; rehabilitation
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Recovery of locomotion has been considered unattainable following a clinically complete or severe incomplete spinal cord injury even after conventional therapy. However, the locomotion of spinal animals can be improved by training that provides complex temporal patterns of sensory information related to stepping that is interpreted by the spinal cord. This review discusses the evidence that suggests human spinal networks can integrate and interpret complex sensory signals to produce functional efferent output and adapt to repetitive training. Locomotor training, a new rehabilitative approach, is based on principles that promote the movement of limbs and trunk to generate sensory information consistent with locomotion to improve the potential for the recovery of walking after neurologic injury.
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