Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 24, Issue 5, Pages 385-389Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/BF02975180
Keywords
antitumor agents; cyclopentaquinoline derivatives; cytotoxic activity; doxorubicin; TAS-103
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Twelve 4-substituted cyclopenta[c]quinoline derivatives were synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines (HOP62, SK-OV-3, MD-MB-468 and T-47D). The compounds 6c and 6e bearing p-anisidine and pyrrolidine side chain were more active than the others.
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