Journal
BEHAVIOR GENETICS
Volume 44, Issue 2, Pages 91-96Publisher
SPRINGER
DOI: 10.1007/s10519-014-9644-z
Keywords
Height; Intelligence; Molecular genetics; Genetic correlation; Generation Scotland
Funding
- Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6]
- Scottish Funding Council [HR03006]
- UK Medical Research Council (MRC)
- MRC
- Alzheimer Scotland
- BBSRC
- Chief Scientist Office [CZD/16/6/4] Funding Source: researchfish
- Medical Research Council [G0100266, MR/K026992/1] Funding Source: researchfish
- MRC [G0100266] Funding Source: UKRI
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Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49-63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences.
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