Journal
INTENSIVE CARE MEDICINE
Volume 27, Issue 10, Pages 1567-1577Publisher
SPRINGER
DOI: 10.1007/s001340101050
Keywords
critical illness; thyroid hormones; growth hormone; prolactin; cortisol; synacthen; relative adrenal insufficiency syndrome; insulin resistance; norepinephrine; intensive care
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Critically ill patients show a variety of hormonal changes that appear to differ considerably in acute and prolonged critical illness. Whether these endocrine alterations serve as physiological adaptation or contribute to further deterioration remains an intriguing question. We review the recent literature and discuss whether measuring circulating hormone concentrations, performing stimulation tests, and intervening with hormone substitution could contribute to the recovery of critically ill patients.
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