Journal
JOURNAL OF COLLOID AND INTERFACE SCIENCE
Volume 242, Issue 1, Pages 272-276Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1006/jcis.2001.7787
Keywords
PEGylated dendrimers; drug delivery; fluorescence spectroscopy; pyrene; betamethasone corticosteroids
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PEGylated diaminobutane poly(propylene imine) dendrimers were investigated as prospective drug delivery systems. Solubilization and release properties of these dendrimeric derivatives were investigated by fluorescence spectroscopy by employing pyrene as probe. The prospective application of the same dendrimers as drug carriers was first evaluated by incorporating within their interior sufficient concentrations of betamethasone corticosteroids. (C) 2001 Academic Press.
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