Journal
PHYTOCHEMISTRY
Volume 58, Issue 3, Pages 517-523Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0031-9422(01)00260-6
Keywords
Laurencia; rhodomelaceae; red alga; sesquiterpene; C-15 acetogenin; halogenated compound; chemotaxonomy; antibacterial activity
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The chemical compositions of five species of the red algal genus Laurencia from coastal waters of Okinawa Prefecture, Japan, have been investigated. A halogenated C-15 acetogenin, (12E)-lembyne-A, was isolated front L. mariannensis, and a halogenated sesquiterpene, (6R,9R,10S)-10-bromo-9-hydroxy-chamigra-2,7(14)-diene, was first found from L. majuscula as a naturally occurring compound. Laurencia nidifica yielded previously known laurinterol and isolaurinterol. Samples of L. cartilaginea and L. concreta afforded no halogenated metabolites. The structures of these halogenated metabolites as well as their antibacterial activity against some marine bacteria are reported., (C) 2001 Elsevier Science Ltd. All rights reserved.
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