Journal
JOURNAL OF NATURAL PRODUCTS
Volume 64, Issue 10, Pages 1357-1359Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np0102859
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Funding
- NCI NIH HHS [R15 CA 56911-01A1] Funding Source: Medline
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Bioassay-guided investigation of the ethanol extract of Peperomia galioides using a tensile strength method in mice as a monitor led to the isolation of epi-alpha -bisabolol (1) (ED50 155 mug/mL). An in vivo healing study of selected commercially available monoterpenoids yielded two bioactive compounds, alpha -bisabolol (2) and a-terpineol (3) (ED50 of 228 and 240 mg/g mouse, respectively).
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