Journal
ORGANIC LETTERS
Volume 3, Issue 20, Pages 3169-3171Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0164839
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- NIGMS NIH HHS [GM51982] Funding Source: Medline
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GRAPHICS The intramolecular Mannich reaction of delta -amino beta -keto esters with aldehydes and ketones is a new methodology for the synthesis of polysubstituted piperidines and is illustrated by the concise asymmetric synthesis of the dendrobate alkaloid (+)-241D and its C-4 epimer.
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