Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 66, Issue 21, Pages 7125-7128Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo010573+
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The Suzuki coupling reaction has been used extensively for the synthesis of a wide variety of unsymmetrical biaryl compounds. We have extended this reaction to demonstrate the utility of preparing monophenyl-, diphenyl-, or triphenylpyrimidine depending on the reaction conditions. Further, it has been shown that chloropyrimidine substrates are preferable over iodo-, bromo-, or fluoropyrimidines.
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