4.6 Article

Host-Salmonella interaction:: human trials

Journal

MICROBES AND INFECTION
Volume 3, Issue 14-15, Pages 1271-1279

Publisher

EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S1286-4579(01)01487-3

Keywords

Salmonella typhi; typhoid vaccines; immunity, humoral; immunity, cellular; T-lymphocytes, cytotoxic

Funding

  1. NIAID NIH HHS [R01-AI 36525, R01-AI 29471, N01-AI 65299, N01-AI 54251] Funding Source: Medline

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Human clinical trials, including experimental challenges of volunteers with pathogenic Salmonella enterica serovar Typhi, small phase I and II trials that monitor the immune responses to vaccines, and large-scale controlled field trials that assess vaccine efficacy under conditions of natural challenge, have helped elucidate the interactions between Salmonella typhi and human hosts. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

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