4.8 Article

Assembly of microarrays for genome-wide measurement of DNA copy number.

Journal

NATURE GENETICS
Volume 29, Issue 3, Pages 263-264

Publisher

NATURE AMERICA INC
DOI: 10.1038/ng754

Keywords

-

Funding

  1. NCI NIH HHS [CA80314, CA58207, CA84118, CA83040] Funding Source: Medline
  2. NICHD NIH HHS [HD17665] Funding Source: Medline

Ask authors/readers for more resources

We have assembled arrays of approximately 2,400 BAC clones for measurement of DNA copy number across the human genome. The arrays provide precise measurement (s.d. of log(2) ratios=0.05-0.10) in cell lines and clinical material, so that we can reliably detect and quantify high-level amplifications and single-copy alterations in diploid, polyploid and heterogeneous backgrounds.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available