Journal
AUTOPHAGY
Volume 10, Issue 4, Pages 549-551Publisher
LANDES BIOSCIENCE
DOI: 10.4161/auto.28448
Keywords
amphisome; lysosome; phagophore; stress; xenophagy
Categories
Funding
- NIAID NIH HHS [R01 AI042999, AI042999, R01 AI111935, AI111935] Funding Source: Medline
- NIGMS NIH HHS [GM053396, R01 GM053396] Funding Source: Medline
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When an autophagosome or an amphisome fuse with a lysosome, the resulting compartment is referred to as an autolysosome. Some people writing papers on the topic of autophagy use the terms autolysosome and autophagolysosome interchangeably. We contend that these words should be used to denote 2 different compartments, and that it is worthwhile maintaining this distinctionthe autophagolysosome has a particular origin in the process of xenophagy that makes it distinct from an autolysosome.
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