Journal
AUTOPHAGY
Volume 9, Issue 5, Pages 633-634Publisher
LANDES BIOSCIENCE
DOI: 10.4161/auto.24146
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Funding
- NHLBI NIH HHS [R01 HL094586, R01HL094586] Funding Source: Medline
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Autophagy has emerged as a significant innate immune response to pathogens. Typically, autophagosomes deliver their contents to lysosomes for degradation. Some pathogens such as Salmonella enterica serovar Typhimurium succumb to autophagy and are transported to lysosomes for degradation. Yet, many professional pathogens, including Legionella pneumophila and Burkholderia cenocepacia, subvert this pathway exploiting autophagy to their advantage.
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