Journal
AUTOPHAGY
Volume 6, Issue 7, Pages 979-980Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/auto.6.7.13118
Keywords
autophagy; cell death; LC3; protein turnover; ubiquitin
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Funding
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM066287] Funding Source: NIH RePORTER
- NIGMS NIH HHS [R01 GM066287] Funding Source: Medline
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Ubiquilin proteins are conserved across all eukaryotes and function in the regulation of protein degradation. We found that ubiquilin functions to regulate macroautophagy and that the protein is also a substrate of chaperone-mediated autophagy.
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