4.5 Article

Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child

Journal

PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 20, Issue 11, Pages 1083-1086

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00006454-200111000-00016

Keywords

herpes simplex virus; immunocompromised; cidofovir; foscarnet; acyclovir; resistance; stomatitis; child; acute lymphatic leukemia; bone marrow transplant

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A leukemic child developed recurrent herpes simplex virus lesions shortly after receiving a bone marrow transplant and while taking acyclovir. The isolate was resistant to acyclovir and foscarnet in vitro. The lesions responded to a course of cidofovir.

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