4.4 Article Proceedings Paper

Measuring the elastic properties of protein crystals by brillouin scattering

Journal

JOURNAL OF CRYSTAL GROWTH
Volume 232, Issue 1-4, Pages 498-501

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/S0022-0248(01)01092-2

Keywords

crystal structure; growth from solution; biological macromolecules; lysozyme; proteins

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We report preliminary measurements of the elastic properties of tetragonal lysozyme crystals using Brillouin scattering. This microscopic, non-contact technique is ideally suited for study of fragile, optically transparent macromolecular crystals. Brillouin scattering should allow much more complete characterization of crystal elasticity, and provide a novel probe of intermolecular interactions, conformation changes, and defect formation. (C) 2001 Elsevier Science B.V. All rights reserved.

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