Journal
NEUROSCIENCE LETTERS
Volume 313, Issue 1-2, Pages 83-87Publisher
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0304-3940(01)02252-2
Keywords
VPS10-domain receptor; western blot analysis; immunohistochemistry; dendrites; murine brain
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The expression of the sorCS1 protein in the central nervous system of adult mice was studied by immunohistochemistry. A detailed mapping revealed a distribution of sorCS1 immunoreactivity in a widespread population of neurons throughout the brain. Two different types of cellular localization were observed. Many neurons exhibited a punctate cytoplasmic staining which extended into the dendrites, in other neurons sorCS1 immunoreactivity was associated with the plasma membrane. This suggests variable functions for sorCS1 in the neurons of the brain. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
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