Journal
TETRAHEDRON
Volume 57, Issue 45, Pages 9309-9315Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(01)00933-4
Keywords
asymmetric reactions; resolution; acylation; amines
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A 3-acyl-2-(N-cyanoimino)oxazolidine derivative was found to serve as an enantioselective acylating agent for sec-alkyl amines. These reagents differentiate the enantiomers of 1-phenylethylamine derivatives up to 85% ee, and the recovered chiral auxiliary is reusable. (C) 2001 Elsevier Science Ltd. All rights reserved.
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