Journal
NEURON
Volume 32, Issue 3, Pages 451-461Publisher
CELL PRESS
DOI: 10.1016/S0896-6273(01)00482-2
Keywords
-
Categories
Funding
- NEI NIH HHS [R01 EY011358, EY11358, P30 EY12196, EY12231, EY12600, R01 EY004939, R01 EY012231, EY07543, EY04939, EY01157, EY04876] Funding Source: Medline
Ask authors/readers for more resources
Rods and cones contain closely related but distinct G protein-coupled receptors, opsins, which have diverged to meet the differing requirements of night and day vision. Here, we provide evidence for an exception to that rule. Results from immunohistochemistry, spectrophotometry, and single-cell RT-PCR demonstrate that, in the tiger salamander, the green rods and blue-sensitive cones contain the same opsin. In contrast, the two cells express distinct G protein transducin a subunits: rod a transducin in green rods and cone a transducin in blue-sensitive cones. The different transducins do not appear to markedly affect photon sensitivity or response kinetics in the green rod and blue-sensitive cone. This suggests that neither the cell topology or the transducin is sufficient to differentiate the rod and the cone response.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available