Journal
NUCLEIC ACIDS RESEARCH
Volume 29, Issue 22, Pages 4633-4642Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/29.22.4633
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The repetitive structure of genomic DNA holds many, secrets to be discovered. A systematic study of repetitive DNA on a genomic or inter-genomic scale: requires extensive algorithmic support. The REPuter program described herein was designed to serve as a fundamental tool in such studies. Efficient and complete detection of various types of repeats is provided together with an evaluation of significance and interactive visualization. This article circumscribes the wide scope of repeat analysis using applications in five different areas of sequence analysis: checking fragment assemblies, searching for low copy repeats, finding unique: sequences, comparing gene structures and mapping of cDNA/EST sequences.
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