Journal
JOURNAL OF FLUORINE CHEMISTRY
Volume 112, Issue 1, Pages 123-131Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/S0022-1139(01)00477-8
Keywords
amides; amines; amino alcohols; enones; esters; nucleophilic trifluoromethylation; TMSCF3
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The paper reviews our recent findings on the trifluoromethylation of organic compounds using TMSCF3. Direct preparation of trifluoromethylated ketones from esters, amides from alcohols and an-lines from imines is described. Trifluoromethylated amino alcohols are also prepared using a three-component condensation chemistry. (C) 2001 Elsevier Science B.V. All rights reserved.
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