Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 12, Issue 6, Pages 574-586Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0958-1669(01)00265-8
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Synthetic building blocks bearing hydroxylated chiral centers are important targets for biocatalysis. Many C-C bond forming enzymes have recently been investigated for new applications and new strategies towards the synthesis of natural products and related oxygenated compounds. Several old catalysts have been studied to increase our functional knowledge of natural aldolase-type enzymes, and new mutated catalysts or catalytic antibodies have been tested for their synthetic utility.
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