Journal
FARMACO
Volume 56, Issue 12, Pages 953-958Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/S0014-827X(01)01167-3
Keywords
1,2,4-triazole derivatives; synthesis; antibacterial, antifungal; antimycobacterial activities
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5-(4-Pyridinyl)-4-substituted-2,4-dihydro-3H-1,2,4-triazole-3-thiones and 5-(4-pyridinyl)-4-substituted-3-(benzoylmethyl)thio 4H-1,2,4-triazoles were synthesized. The structures of original nine compounds were confirmed by IR, H-1 NMR, mass spectral methods and elemental analysis. The antibacterial, antifungal and antimycobacterial activities, together with those of known intermediate 1,4-disubstituted thiosemicarbazides, were reported. (C) 2001 Elsevier Science S.A. All rights reserved.
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