Journal
TRENDS IN NEUROSCIENCES
Volume 24, Issue 12, Pages 706-712Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0166-2236(00)01954-8
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A fundamental problem in neuroscience has been the creation of suitable in vivo model systems to study basic neurological phenomena and pathology of the central nervous system (CNS). Somatic cell genetic engineering with viral vectors provides a versatile tool to model normal brain physiology and a variety of neurological diseases.
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