4.5 Review

Statistical methods for the analysis and presentation of the results of bone marrow transplants. Part 2: Regression modeling

Journal

BONE MARROW TRANSPLANTATION
Volume 28, Issue 11, Pages 1001-1011

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bmt.1703271

Keywords

Cox model; proportional hazards models; fixed and time-dependent covariate

Funding

  1. NCI NIH HHS [R01-CA54706-07] Funding Source: Medline

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In this paper, we address methods of multivariate regression. We discuss the value of regression compared to matched pairs analysis, methods of coding variables, basic concepts of the Cox model and interpretation of results of the Cox model. We present methods of handling variables whose effect changes with time. We present methods to check the assumptions of the Cox regression. Finally, and perhaps most importantly, we provide suggestions for presenting the results in clear and thorough tables and graphs.

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