Journal
JOURNAL OF ETHNOPHARMACOLOGY
Volume 78, Issue 2-3, Pages 133-137Publisher
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0378-8741(01)00326-9
Keywords
Mangifera indica; Cell mediated immunity; humoral immunity; immunomodulatory
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Mangifera indica Linn, a plant widely used in the traditional medicinal systems of India, has been reported to possess antiviral, antibacterial and anti-inflammatory activities. In the present study, the alcoholic extract of stem bark of Mangifera indica Linn (Extract I containing mangiferin 2.6%), has been investigated for its effect on cell mediated and humoral components of the immune system in mice. Administration of test extract I produced increase in humoral antibody (HA) titre and delayed type hypersensitivity (DTH) in mice. It is concluded that test extract I is a promising drug with immunostimulant properties. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
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