Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 11, Issue 6, Pages 620-626Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(00)00244-6
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An increasingly comprehensive assessment is being developed of the extent and potential significance of lateral gene transfer among microbial genomes. Genomic sequences can be identified as being of putatively lateral origin by their unexpected phyletic distribution, atypical sequence composition, differential presence or absence in closely related genomes, or incongruent phylogenetic trees. These complementary approaches sometimes yield inconsistent results. Not only more data but also quantitative models and simulations are needed urgently.
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